Transcatheter tricuspid valve repair was associated with improved 1-year survival compared with screen-fail patients only when tricuspid regurgitation was reduced to moderate or less.
Observational (n=547)
Yes
Does transcatheter tricuspid valve repair improve 1-year survival in patients with severe or greater tricuspid regurgitation compared to screen-failed patients?
Transcatheter tricuspid valve repair improves 1-year survival compared to screen failure, provided procedural success (residual TR ≤ moderate) is achieved.
p-value: p==0.74
BACKGROUND: Observational registries have shown improved survival among patients with severe or greater tricuspid regurgitation (TR) undergoing transcatheter tricuspid valve repair (TTVr) compared with conservative management. However, it remains unclear whether this survival benefit persists when specifically comparing patients undergoing TTVr with those who screen failed. METHODS: We conducted a retrospective analysis of 547 patients from the TriSelect registry evaluated for TTVr-either transcatheter tricuspid valve edge-to-edge repair or direct transcatheter tricuspid valve annuloplasty at 3 tertiary centers in the United States and Germany between 2016 and 2021. The end point of 1-year survival was stratified by treatment group (TTVr versus screen fail) and procedural success (residual TR ≤ moderate versus > moderate). RESULTS: =0.74). CONCLUSIONS: In this registry-based analysis, TTVr was associated with improved 1-year survival compared with screen-fail patients, but only when TR was reduced to moderate or less. These findings highlight the critical importance of achieving procedural success with a TTVr along with early referral and transcatheter tricuspid valve intervention device selection.
Rudolph et al. (Tue,) conducted a observational in Severe or greater tricuspid regurgitation (n=547). Transcatheter tricuspid valve repair (TTVr) vs. Screen fail was evaluated on 1-year survival (p==0.74). Transcatheter tricuspid valve repair was associated with improved 1-year survival compared with screen-fail patients only when tricuspid regurgitation was reduced to moderate or less.