To explore a dual-network hydrogel's potential for repairing infected wounds with antibacterial and regenerative functions.
Developed a dual-crosslinked hydrogel using SIS collagen and chitosan.
Evaluated the antibacterial and regenerative properties of the hydrogel in vitro and in vivo.
Compared the hydrogel's effectiveness to traditional wound dressings.
The dual-network hydrogel exhibited significant antibacterial activity against common pathogens.
The hydrogel promoted faster wound healing compared to control dressings.
SIS collagen and chitosan synergistically improved the regenerative properties of the dressing.
Abstract
dual-crosslinked hydrogel, leveraging the synergistic effect of SIS collagen and copper ions, represented a promising functional dressing for managing infected wounds.