May 20, 2020Open Access

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

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Abstract

reductions in median viral loads in bronchoalveolar lavage and nasal mucosa, respectively, as compared with viral loads in sham controls. Vaccine-elicited neutralizing antibody titers correlated with protective efficacy, suggesting an immune correlate of protection. These data demonstrate vaccine protection against SARS-CoV-2 in nonhuman primates.

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Yu et al. (Wed,) studied this question.

synapsesocial.com/papers/69fc945b4f95092fbe78e88c https://doi.org/https://doi.org/10.1126/science.abc6284

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