Key points are not available for this paper at this time.
CREB binding protein (CBP) and p300 were both identified initially in protein interaction assays-the former through its association with the transcription factor CREB The recognition that these two proteins, one involved in transcription and the other in cell transformation, had highly conserved sequences suggested that they had the potential to participate in a variety of cellular functions (Fig. Several excellent reviews
Goodman et al. (Sat,) studied this question.