June 1, 2022

Transition Metal-Catalyzed Biaryl Atropisomer Synthesis via a Torsional Strain Promoted Ring-Opening Reaction

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Abstract

-substituted biaryl atropisomers with high enantiopurity on the basis of the above-mentioned torsional strain-promoted ring-opening coupling strategy. In the last part, the torsional strain energies are also discussed with the aid of density functional theory (DFT) calculations.

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Zhang et al. (Wed,) studied this question.

synapsesocial.com/papers/69ffeb74b124fe581985af34 https://doi.org/https://doi.org/10.1021/acs.accounts.2c00175

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