During incremental exercise in healthy young individuals, the temporal attainment of peak cardiac output and lowest systemic vascular resistance were positively associated (r = 0.74, p = 0.005).
12 healthy young individuals (7 male, 5 female), mean age 26 ± 3 years.
Maximal incremental exercise test on a supine, tilted ergometer to volitional exhaustion.
Individual hemodynamic thresholds during exercise (Hem-TRex) of cardiac output (Q), systemic vascular resistance (SVR), and mean arterial pressure (MAP).surrogate
The temporal attainment of peak cardiac output and lowest systemic vascular resistance during exercise are interdependent and relate inversely to the timing of peak mean arterial pressure.
Effect estimate: r = 0.74
p-value: p=0.005
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Fabian Spahiu
Leibniz University Hannover
Max Hagemann
Leibniz University Hannover
Michelle Ottlik
Leibniz University Hannover
Journal of Human Hypertension
University of Tasmania
Leibniz University Hannover
Cardiff Metropolitan University
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Spahiu et al. (Wed,) conducted a letter in Healthy (n=12). Incremental exercise was evaluated on Association between temporal occurrences of Hem-TRex Q (cardiac output) and Hem-TRex SVR (systemic vascular resistance) (r = 0.74, p=0.005). During incremental exercise in healthy young individuals, the temporal attainment of peak cardiac output and lowest systemic vascular resistance were positively associated (r = 0.74, p = 0.005).
synapsesocial.com/papers/6a025effc9581ed855361b53 — DOI: https://doi.org/10.1038/s41371-026-01155-4