In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines

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Abstract

Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

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Blackburn et al. (Tue,) studied this question.

synapsesocial.com/papers/6a03caf4e2ca96d80dd7c0e7 https://doi.org/https://doi.org/10.1021/ol015819b

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