The research aims to understand how mutations in the promoter region increase β-cypermethrin resistance in Plutella xylostella.
Investigated mutations in the promoter region of PxαE27
Analyzed the role of transcription factors in CarE expression
Evaluated the impact of CarE levels on insecticide resistance
Mutations in the promoter region significantly increased CarE expression levels
Enhanced β-cypermethrin resistance observed with specific transcription factor recruitment
Findings suggest new strategies for managing insecticide resistance in Plutella xylostella
Abstract
-regulatory mutations recruit specific transcription factors to elevate CarE expression and drive insecticide resistance, providing a mechanistic basis for potential resistance management strategies.