One-Step Synthesis of Zolpidem and Its Analogues via Visible Light Induced Coupling of Imidazo1,2-αpyridines with 2-Bromoacetamides

Key Points

• To develop an efficient method for synthesizing zolpidem and its analogues using visible light.
• Utilized blue LED irradiation for the coupling process.
• Combined imidazo[1,2-α]pyridines with 2-bromoacetamides.
• Established a one-step synthesis approach.
• Successfully synthesized zolpidem and several analogues.
• Demonstrated enhanced efficiency compared to traditional methods.
• The reaction was carried out under mild conditions.