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pK's of Nucleic Acid Components as a Function of Temperature | Synapse

May 16, 2026Open Access

pK's of Nucleic Acid Components as a Function of Temperature

Key Points

This research aims to study the pK values of deoxynucleic acid components under varying temperatures.
Examined pK's of -N1H- groups for several deoxynucleic acid components at different temperatures.
Analyzed thymidine, thymidylic acid, deoxyguanosine, and deoxyguanylic acid (5') in the investigation.
Calculated △Ĥ's for the ionizations from the obtained pK values.
Identified temperature-dependent changes in the pK values for the studied components.
Determined ionization enthalpies (△Ĥ's) related to temperature variations.

Abstract

The pK's of the -N1H- groups for the several deoxynucleic acid components have been studied as a function of temperature. From this the △Ĥ's for the ionizations are obtained. The components studied were thymidine, thymidylic acid, deoxyguanosine, and deoxyguanylic acid (5').

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Cite This Study

Atkinson, Thomas Vincent, Jr. (Thu,) studied this question.

synapsesocial.com/papers/6a0809bea487c87a6a40b970 https://doi.org/https://doi.org/10.7907/s176-y927