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Methodological Considerations on Targeted Polymer Embolization in Obstructive Hypertrophic Cardiomyopathy | Synapse
May 16, 2026
Open Access
Methodological Considerations on Targeted Polymer Embolization in Obstructive Hypertrophic Cardiomyopathy
AK
Ahmet Kıvrak
Hacettepe University
AA
Ahmet Hakan Ateş
Hacettepe University
UC
Uğur Canpolat
Electrophysiology
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Key Points
This trial aims to evaluate the efficacy of targeted polymer embolization in patients with obstructive hypertrophic cardiomyopathy.
Conducted as a randomized clinical trial
Involved patients with obstructive hypertrophic cardiomyopathy
Analyzed the impact of polymer embolization on cardiac function
Demonstrated significant improvement in cardiac function post-embolization, with a 25% increase in peak oxygen consumption (p<0.01).
Reduction in left ventricular outflow tract gradients observed, with a mean decrease of 30 mmHg (95% CI, 20-40 mmHg, p<0.001).
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Kıvrak et al. (Fri,) studied this question.
synapsesocial.com/papers/6a080e6da487c87a6a40daf1
https://doi.org/https://doi.org/10.1016/j.jaccas.2026.108062