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In this paper, we present a new method for reconstructing 3D left ventricular myocardial strain from tagged magnetic resonance (MR) image data with a 3D B-spline deformation model. The B-spline model is based on a cylindrical coordinate system that more closely fits the morphology of the myocardium than previously proposed Cartesian B-spline models and does not require explicit regularization. Simulation results demonstrate that the reconstructed strains are robust to the center of the cylindrical coordinate system. We also validate our method by reconstructing strains from imaging studies of a normal human volunteer and a patient with an antero-septal myocardial infarction.
Deng et al. (Wed,) studied this question.
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