Why the study?
Structural alterations in the resistance vasculature in essential hypertension were traditionally attributed to vascular growth, but could alternatively be caused by vascular remodelling.
Design
Review
Key result
Vascular remodelling, involving the rearrangement of material around a smaller lumen, is reviewed as an important factor in the pathogenesis of essential hypertension.
Authors
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Remodeling may explain resistance-vessel changes in hypertension; leaves open the dominant mechanism and any therapeutic implications.
This review highlights vascular remodelling as a key mechanism in the structural alterations of resistance vasculature in essential hypertension.
Michael J. Mulvany (1993) conducted a review in Essential hypertension. Vascular remodelling, involving the rearrangement of material around a smaller lumen, is reviewed as an important factor in the pathogenesis of essential hypertension.