Idiopathic Hypertrophic Subaortic Stenosis in Two Elderly Siblings

THIS communication concerns 2 sisters, sixty-eight and sixty-three years of age, who first had signs and symptoms of idiopathic hypertrophic subaortic stenosis late in life. Two previous generations of the family had apparently been afflicted by the disease at a similar time in life. Although the familial nature1 2 3 4 5 6 7 8 and variable onset of idiopathic hypertrophic subaortic stenosis1 , 9 10 11 12 13 have been well documented, the late appearance of the disease in this family with survival into the seventh decade is distinctly unusual.Case ReportsCase 1. A 68-year-old woman was first seen in October, 1964. She had been in good health until the age . . .