In vascular surgery patients, the lowest functional status at discharge was associated with increased odds of 90-day mortality (OR 3.41; 95% CI 1.70-6.84) compared to the highest functional status.
Cohort (n=2,318)
No
Does the lowest functional status at discharge increase 90-day mortality and 30-day readmission in adult non-cardiac vascular surgery patients?
In vascular surgery patients surviving hospitalization, poor functional status at discharge is strongly associated with increased 90-day mortality and 30-day readmission.
Effect estimate: OR 3.41 (95% CI 1.70-6.84)
BACKGROUND: We aimed to determine the correlation between the functional status at discharge in non-cardiac vascular surgery patients and the out-of-hospital mortality. METHODS: We performed a retrospective cohort study including adult non-cardiac vascular surgery patients (open, endovascular and venous procedures) surviving hospitalization in Boston, Massachusetts, USA. The exposure of interest was functional status determined by a licensed physical therapist at hospital discharge and rated based on qualitative categories adapted from the Functional Independence Measure. The primary outcome was all cause 90-day mortality after hospital discharge. The secondary outcome was readmission within 30days. Adjusted odds ratios were estimated by multivariable logistic regression models. RESULTS: This cohort included 2318 patients (male 51%; mean age 61 ± 17.7). After evaluation by a physiotherapist, 425 patients scored the lowest functional status, 631 scored moderately low, 681 moderately high and 581 scored the highest functional status. The lowest functional status was associated with a 3.41-fold increased adjusted odds for 90-day mortality (95%CI, 1.70-6.84) compared to patients with the highest functional status. When excluding venous intervention patients, the adjusted odds ratio was 6.76 (95%CI, 2.53-18.12) for the 90-day mortality post-discharge. The adjusted odds for readmission within 30-days was 1.5-fold increase in patients with the lowest functional status (95%CI, 1.04-2.20). CONCLUSIONS: In vascular surgery patients surviving hospitalization, functional status is strongly associated with out-of-hospital mortality and readmission rate. Future trials could provide evidence if improvement of functional status could prevent adverse outcomes in the postoperative setting.
Meijenfeldt et al. (Mon,) conducted a cohort in Non-cardiac vascular surgery (n=2,318). Lowest functional status vs. Highest functional status was evaluated on All cause 90-day mortality after hospital discharge (OR 3.41, 95% CI 1.70-6.84). In vascular surgery patients, the lowest functional status at discharge was associated with increased odds of 90-day mortality (OR 3.41; 95% CI 1.70-6.84) compared to the highest functional status.