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Children being treated with methylphenidate or dextroamphetamine for minimal brain dysfunction syndrome and subsequent hyperkinetic impulse disorder may develop annoying side effects. A pilot study substituting caffeine, in the form of two cups of regular coffee a day, suggests that caffeine may be a suitable alternative to Schedule II drugs. The author points out the advantages of treatment with caffeine and suggests some specific aspects for further studies in this area.
Robert C. Schnackenberg (Sun,) studied this question.