Echocardiographic, haemodynamic, and angiographic evaluation of 14 patients with hypertrophic cardiomyopathy revealed an intraventricular gradient in 86% and asymmetrical septal hypertrophy in 79%.
Observational (n=14)
This early case series characterizes the frequency of key echocardiographic and hemodynamic abnormalities, such as asymmetrical septal hypertrophy and intraventricular gradients, in patients with hypertrophic cardiomyopathy.
Attempts to identify a pathognomonic abnormality in 'idiopathic hypertrophic subaortic stenosis' date back to the time of its recognition. We examined the echocardiographic, haemodynamic, and angiographic features of 14 consecutive patients in whom the clinical diagnosis was supported by the presence of both asymmetrical septal hypertrophy and systolic anterior movement of the anterior leaflet of the mnitral valve on the echocardio- gram, or an intraventricular pressure gradient at rest or with provocation. A gradient was shown in 12 cases (86%), the Brockenbrough or postextrasystolic response in 9 (64%), asymmetrical septal hypertrophy in 11 (79%), systolic anterior movement in 7 (50%), and left ventricular cavity obliteration in systole in 12 (86%).
Chahine et al. (Thu,) conducted a observational in Hypertrophic cardiomyopathy (n=14). Echocardiographic, haemodynamic, and angiographic evaluation of 14 patients with hypertrophic cardiomyopathy revealed an intraventricular gradient in 86% and asymmetrical septal hypertrophy in 79%.