Catechu, a conventional herbal product derived from Acacia catechu, is recognized for its wide-ranging therapeutic properties, including antioxidant, antimicrobial, and anti-inflammatory effects. This study aimed to develop and evaluate a topical herbal gel containing catechu extract to harness its medicinal potential for dermal applications. The gel was formulated using suitable gelling agents and excipients to ensure optimal consistency, stability, and ease of application. The comprehensive evaluation of the gel included assessments of appearance, pH, viscosity, distribution capability, homogeneity, extrudability, and stability under specified conditions. The formulated catechu gel exhibited a visually desirable and homogeneous structure with a pH corresponding to skin physiology, ensuring minimal irritation. Rheological analysis demonstrated suitable viscosity, facilitating easy spreadability and dispensability, which are important for patient compliance and comfort. Stability studies established the physical and chemical consistency of the gel over the testing period, with no substantial changes in the key parameters. If applicable, drug release studies indicated the sustained release of active constituents, supporting prolonged therapeutic action. These findings validate the physicochemical properties and stability of the catechu-based gel for topical use. The developed formulation offers a promising herbal alternative for treating skin conditions by leveraging the biologically active profile of Cat. This study highlights the potential pharmaceutical application of catechu gel as an effective, patient-friendly, external herbal formulation with significant therapeutic benefits.
1Dr. M. J. Patil, 2Ruchita R. Bhagwat, 3*Shruti Vasant Marale, 4Dhiraj Yogesh Kolekar (Sat,) studied this question.