Nitroglycerin and organic nitrates act as potent vascular dilators on venous and arterial circulation, and are increasingly used for angina, heart failure, and acute myocardial infarction.
Nitroglycerin and organic nitrates are potent vascular dilators with established roles in the management of angina pectoris, congestive heart failure, and acute myocardial infarction.
NITROGLYCERIN and organic nitrates are being used in an increasing variety of cardiac conditions in addition to angina pectoris. Nitrate therapy is becoming routine in the vasodilator treatment of congestive heart failure, and under diverse experimental conditions it appears to be effective in the treatment of acute myocardial infarction.Pharmacology of NitratesNitroglycerin is a potent vascular dilator exerting its strongest effect on the venous system (capacitance vessels) and a lesser effect on the arterial circulation (resistance vessels). The drug acts at specific nitrate receptors in the vascular smooth-muscle wall to trigger vascular relaxation.1 All nitrate esters produce the same . . .
Jonathan Abrams (Thu,) conducted a review in Cardiac conditions including angina pectoris, congestive heart failure, and acute myocardial infarction. Nitroglycerin and organic nitrates was evaluated. Nitroglycerin and organic nitrates act as potent vascular dilators on venous and arterial circulation, and are increasingly used for angina, heart failure, and acute myocardial infarction.