Cardioneuroablation using epicardial pulsed field ablation is reviewed as a potential treatment for atrial fibrillation, highlighting insights from pre-clinical and early clinical studies.
Does cardioneuroablation using epicardial pulsed field ablation treat atrial fibrillation?
Epicardial pulsed field ablation is an emerging cardioneuroablation technique for modulating the cardiac autonomic nervous system to treat atrial fibrillation.
Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting millions of people worldwide. The cardiac autonomic nervous system (ANS) is widely recognized as playing a key role in both the initiation and propagation of AF. This paper reviews the background and development of a unique cardioneuroablation technique for the modulation of the cardiac ANS as a potential treatment for AF. The treatment uses pulsed electric field energy to selectively electroporate ANS structures on the epicardial surface of the heart. Insights from in vitro studies and electric field models are presented as well as data from both pre-clinical and early clinical studies.
O’Brien et al. (Mon,) conducted a review in Atrial Fibrillation. Cardioneuroablation using epicardial pulsed field ablation was evaluated. Cardioneuroablation using epicardial pulsed field ablation is reviewed as a potential treatment for atrial fibrillation, highlighting insights from pre-clinical and early clinical studies.
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