Neuronal Substrate of Classical Conditioning in the Hippocampus

Key Points

• This research aims to investigate the neuronal responses in the hippocampus during classical conditioning.
• Recorded neuronal activity in the dorsal hippocampus of rabbits during classical conditioning.
• Utilized tone as the conditioned stimulus and corneal air puff as the unconditioned stimulus.
• Compared responses in animals trained with paired stimuli to control animals with unpaired stimuli.
• Early in training, hippocampal neurons create a temporal model of the behavioral response.
• This hippocampal response is absent in control animals given unpaired stimuli.