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Part 1 Epidemiology and natural history: measurement of blood pressure definitions of hypertension risks of hypertension determinants of blood pressure. Part 2 Mechanisms of blood pressure control: cardiac output and regulation venous circulation vasodilators and vasoconstrictors central regulation baroreceptors renin-angiotensin system other regulatory factors. Part 3 Pathogenesis and experimental models: experimental models physiology mechanisms of blood pressure control cellular changes. Part 4 Pathological consequences: vascular hypertrophy fibrinoid necrosis microangiopathic haemolytic anaemia arteriosclerosis atheroma cardiac effects CNS effects renal effects. Part 5 Known causes of hypertension: the nervous system the kidneys the endocrine system coarctation pregnancy drugs. Part 6 Clinical subgroups: children pregnancy the elderly hypertensive emergencies. Part 7 History and examination: medical, drug and family histories examination. Part 8 Investigation of the patient: urine and blood tests chest X-ray, ECG, ultrasound, pyelography, isotope scannings, CT scannings, plasma renin activity, gamma camera scanning and IVDSA pharmacological tests. Part 9 Drug action: diuretics - adrenoreceptor antagonists vasodilators calcium entry blockers inhibitors of the renin-angiotensin system - blockers centrally acting drugs ganglion blockers adrenergic neurone blockers new agents. Part 10 Treatment: data from the trials non-pharmacological methods - weight loss, sodium intake, potassium intake, calcium intake, alcohol intake, diet, exercise, yoga and relaxation pharmacological treatment - drug combinations, adverse effects special categories.
Ray W. Squires (Sun,) studied this question.
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