Acute post-exercise decrease in systolic blood pressure independently predicted the 6-month training-induced reduction in resting systolic blood pressure in patients with coronary artery disease (β= 0.26).
Cohort (n=116)
No
Does acute post-exercise change in blood pressure predict exercise training responses in resting SBP in patients with coronary artery disease?
Acute post-exercise decrease in systolic blood pressure predicts the magnitude of resting blood pressure reduction following a 6-month exercise training program in patients with coronary artery disease.
Effect estimate: β= 0.26
p-value: p=0.015
We tested the hypothesis that acute post-exercise change in blood pressure (BP) may predict exercise training responses in BP in patients with coronary artery disease (CAD). Patients with CAD (n = 116, age 62 ± 5 years, 85 men) underwent BP assessments at rest and during 10-min recovery following a symptom-limited exercise test before and after the 6-month training intervention (one strength and 3-4 aerobic moderate-intensity exercises weekly). Post-exercise change in systolic BP (SBP) was calculated by subtracting resting SBP from lowest post-exercise SBP. The training-induced change in resting SBP was -2 ± 13 mmHg (p = 0.064), ranging from -42 to 35 mmHg. Larger post-exercise decrease in SBP and baseline resting SBP predicted a larger training-induced decrement in SBP (β = 0.46 and β = -0.44, respectively, p < 0.001 for both). Acute post-exercise decrease in SBP provided additive value to baseline resting SBP in the prediction of training-induced change in resting SBP (R(2) from 0.20 to 0.26, p = 0.002). After further adjustments for other potential confounders (sex, age, baseline body mass index, realized training load), post-exercise decrease in SBP still predicted the training response in resting SBP (β = 0.26, p = 0.015). Acute post-exercise change in SBP was associated with training-induced change in resting SBP in patients with CAD, providing significant predictive information beyond baseline resting SBP.
Kiviniemi et al. (Mon,) conducted a cohort in Coronary artery disease (n=116). Exercise training vs. Baseline (pre-training) was evaluated on Training-induced change in resting systolic blood pressure predicted by acute post-exercise change in SBP (β= 0.26, p=0.015). Acute post-exercise decrease in systolic blood pressure independently predicted the 6-month training-induced reduction in resting systolic blood pressure in patients with coronary artery disease (β= 0.26).