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October 20, 2019Evidence-based Complementary and Alternative Medicine25 citationsOpen Access

The Effect of Acupuncture and Moxibustion on Heart Function in Heart Failure Patients: A Systematic Review and Meta-Analysis

BLBingxue LiangYCYan CuiLZLu Zhang

Key Result

Acupuncture and moxibustion significantly improved the efficacy rate for treating heart failure compared to traditional treatment alone (OR 2.61; 95% CI 1.84-3.72; p<0.0001).

Study Design

Type

Systematic Review (n=2,499)

Structured PICO

Does acupuncture and moxibustion added to medication improve heart function in patients with heart failure?

P
Population
2,499 patients with heart failure pooled from 32 RCTs
I
Intervention
Acupuncture and moxibustion (A&M) as an adjunctive therapy to medication
C
Comparator
Traditional treatment (medication) alone
O
Outcome
Heart function (assessed by efficacy rate, left ventricular ejection fraction, cardiac output, 6-minute walk test, and brain-type natriuretic peptide)surrogate

Acupuncture and moxibustion as an adjunct to standard medication may improve surrogate markers of heart function and exercise capacity in heart failure patients, though the quality of evidence is limited by methodological flaws in the included trials.

Main Result

Effect estimate: OR 2.61 (95% CI 1.84-3.72)

p-value: p=<0.0001

Limitations

  • Most studies had an unclear risk regarding blinding and allocation concealment
  • Adverse events were inadequately reported in most studies
  • The evidence was inconclusive
  • Unclear risk regarding blinding and allocation concealment in most studies
  • Adverse events inadequately reported
  • Evidence was inconclusive

Abstract

Background . Acupuncture and moxibustion (A 3.72], I 2 = 0%, p0.0001) and a significantly improved left ventricular ejection fraction (LVEF) (mean difference (MD) = 6.34, 95%CI = 4.11, 8.57, I 2 = 93%, p0.0001), cardiac output (CO) (MD = 1.02, 95%CI = 0.65, 1.39, I 2 = 94%, p0.0001), 6-minute walk test (6MWT) (MD = 43.6, 95%CI = 37.43, 49.77, I 2 = 0%, p0.0001), and reduced brain-type natriuretic peptide (BNP) (MD = −227.99, 95%CI = −337.30, −118.68, I 2 = 96%, p0.0001). Adverse events were inadequately reported in most studies. Conclusions . A&M may be a promising intervention as an adjunctive therapy to medication for treating heart failure. However, the evidence was inconclusive. Further large and rigorously designed RCTs are needed for verification.

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Cite This Study

Liang et al. (2019) conducted a systematic review in Heart failure (n=2,499). Acupuncture and moxibustion vs. Traditional treatment was evaluated on Efficacy rate (OR 2.61, 95% CI 1.84-3.72, p=<0.0001). Acupuncture and moxibustion significantly improved the efficacy rate for treating heart failure compared to traditional treatment alone (OR 2.61; 95% CI 1.84-3.72; p<0.0001).

synapsesocial.com/papers/6a10b28149545a83bbee3240https://doi.org/10.1155/2019/6074967
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