The LV-METRIC algorithm for automated left ventricular segmentation was highly correlated with manual tracing for ejection fraction (R2 = 0.97) and required no manual corrections.
Observational (n=38)
Does the LV-METRIC algorithm accurately and reproducibly segment the left ventricular cavity in cine MR images compared to manual tracing and commercial software?
The LV-METRIC algorithm provides accurate, reproducible, and fully automated left ventricular volume measurements from cine MRI without the need for manual corrections.
Effect estimate: R2 = 0.97
UNLABELLED: This retrospective analysis of existing patient data had institutional review board approval and was performed in compliance with HIPAA. No informed consent was required. The purpose of the study was to develop and validate an algorithm for automated segmentation of the left ventricular (LV) cavity that accounts for papillary and/or trabecular muscles and partial voxels in cine magnetic resonance (MR) images, an algorithm called LV Myocardial Effusion Threshold Reduction with Intravoxel Computation (LV-METRIC). The algorithm was validated in biologic phantoms, and its results were compared with those of manual tracing, as well as those of a commercial automated segmentation software (MASS MR Analytical Software System), in 38 subjects. LV-METRIC accuracy in vitro was 98.7%. Among the 38 subjects studied, LV-METRIC and MASS ejection fraction estimations were highly correlated with manual tracing (R(2) = 0.97 and R(2) = 0.95, respectively). Ventricular volume estimations were smaller with LV-METRIC and larger with MASS than those calculated by using manual tracing, though all results were well correlated (R(2) = 0.99). LV-METRIC volume measurements without partial voxel interpolation were statistically equivalent to manual tracing results (P > .05). LV-METRIC had reduced intraobserver and interobserver variability compared with other methods. MASS required additional manual intervention in 58% of cases, whereas LV-METRIC required no additional corrections. LV-METRIC reliably and reproducibly measured LV volumes. SUPPLEMENTAL MATERIAL: http://radiology.rsnajnls.org/cgi/content/full/248/3/1004/DC1.
Codella et al. (Mon,) reported a observational. LV-METRIC algorithm vs. Manual tracing and MASS software was evaluated on Correlation of ejection fraction estimations with manual tracing (R2 = 0.97). The LV-METRIC algorithm for automated left ventricular segmentation was highly correlated with manual tracing for ejection fraction (R2 = 0.97) and required no manual corrections.