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January 1, 1991Stroke399 citationsOpen Access

Death and functional outcome after spontaneous intracerebral hemorrhage. A prospective study of 166 cases using multivariate analysis.

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PDP DaveratJCJ P CastelJDJ. F. Dartigues

Key Points

  • To identify clinical and radiological determinants of early mortality and 6-month functional outcomes following spontaneous intracerebral hemorrhage.
  • Prospective cohort study of N=166 patients admitted to an acute-care stroke unit on day 1 of spontaneous intracerebral hemorrhage.
  • Assessed initial computed tomography (CT) morphology (hemorrhage volume, midline shift, intraventricular extension) and clinical neurological deficits.
  • Evaluated 30-day survival and 6-month functional recovery using multivariable logistic regression analysis.
  • At 6 months, 43% of patients (n=71/166) died, 42% (n=69/166) attained a satisfactory outcome, and 16% (n=26/166) experienced poor functional recovery.
  • Early 30-day survival correlated with initial CT morphologic parameters (hemorrhage size, midline shift, and intraventricular spread), whereas 6-month survival correlated primarily with age.
  • Logistic regression identified five independent predictors of satisfactory 6-month outcome: age (the strongest predictor), hemorrhage size, intraventricular hemorrhage extension, limb paresis, and communication disorders.

Abstract

Using death and functional status as end points, we prospectively analyzed the outcome 6 months after spontaneous intracerebral hemorrhage in 166 patients admitted to an acute-care stroke unit on the first day of their stroke. Seventy-one patients (43%) died, 69 (42%) had a satisfactory outcome, and 26 (16%) had a poor functional outcome. Early (30-day) survival was correlated with morphologic parameters on the initial computed tomogram (hemorrhage size, midline shift, and intraventricular spread of the hemorrhage), while later (6-month) survival was correlated with age. Using logistic regression, we found five independent predictors of satisfactory outcome at 6 months: age, hemorrhage size, intraventricular spread of the hemorrhage, limb paresis, and communication disorders. Of these, age was the most important predictor by far.

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Cite This Study

Daverat et al. (1991) studied this question.

synapsesocial.com/papers/6a11e349997792fb8c8e0b87https://doi.org/10.1161/01.str.22.1.1
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