Central sleep apnea in overweight patients with exacerbated heart failure was associated with significantly lower LVEF compared to obstructive sleep apnea (41.8% vs 49.6%; p=0.013).
Observational (n=61)
No
What is the incidence of sleep apnea and its association with ventricular function in overweight patients with exacerbated heart failure?
In overweight patients with exacerbated heart failure, sleep apnea is highly prevalent, with central sleep apnea being associated with significantly lower left ventricular ejection fraction and worse clinical outcomes compared to obstructive sleep apnea.
Absolute Event Rate: 41.8% vs 49.6%
p-value: p=0.013
Sleep disorders are a common concomitant comorbidity in patients with heart failure. The aims of our study are to determine the incidence and phenotypic characteristics of sleep apnea in overweight patients with exacerbated heart failure and to assess the degree of involvement of systolic and diastolic function impairment in the individual group. From 100 screened patients with heart failure in our department from 2015 to 2017, 61 met the inclusion criteria and participated in the study. 82% (n = 50) of the patients had obstructive sleep apnea (OSA), and 18% (n = 11) had central sleep apnea (CSA). The CSA group had a significantly lower left ventricular ejection fraction (LVEF) than the OSA group (EF% 49.6 ± 8.5 vs 41.8 ± 11.4; p = 0.013). A negative correlation was found between LVEF and the number of central apnea events (r = -0.52; p < 0.001). More frequent hospitalizations for heart failure (HF) and higher mortality rate were found in the CSA group. Screening for sleep apnea in patients with exacerbated heart failure and obesity is necessary for the complex treatment of these patients.
Kalaydzhiev et al. (Tue,) conducted a observational in Exacerbated heart failure and overweight (n=61). Central sleep apnea (CSA) vs. Obstructive sleep apnea (OSA) was evaluated on Left ventricular ejection fraction (LVEF) (p=0.013). Central sleep apnea in overweight patients with exacerbated heart failure was associated with significantly lower LVEF compared to obstructive sleep apnea (41.8% vs 49.6%; p=0.013).