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September 1, 1979Cardiovascular Research

Alterations in left ventricular relaxation and diastolic compliance in congestive cardiomyopathy

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Authors

WGWilliam GrossmanLMLambert P. McLaurinEREllis L. Rolett

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Overview

Diastolic dysfunction may drive symptoms in cardiomyopathy; supports routine assessment but leaves open targeted therapies.

Key Points

  • To assess alterations in active left ventricular relaxation and chamber compliance during diastole in patients with congestive cardiomyopathy.
  • Hemodynamic and left ventricular pressure-volume evaluation of cardiac diastolic mechanics in individuals diagnosed with congestive cardiomyopathy.
  • Patients with congestive cardiomyopathy exhibit marked abnormalities in the rate and extent of active left ventricular relaxation.
  • Ventricular diastolic compliance is altered, leading to elevated filling pressures and abnormal diastolic stiffness throughout ventricular filling.

Cite This Study

Grossman et al. (1979) studied this question.

synapsesocial.com/papers/6a154291b2e0231f15822dd8https://doi.org/10.1093/cvr/13.9.514
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