A review of intimal hyperplasia details its pathology, physiology, pharmacology, cell biology, and molecular biology as a chronic structural lesion developing after vessel wall injury.
Abstract In the current vascular interventional environment, high restenosis rates have increased awareness of the significance of intimal hyperplasia, a chronic structural lesion that develops after vessel wall injury, and which can lead to luminal stenosis and occlusion. Intimal hyperplasia may be defined as the abnormal migration and proliferation of vascular smooth muscle cells with associated deposition of extracellular connective tissue matrix. The pathology of intimal hyperplasia is reviewed with particular attention to its physiology, pharmacology, cell biology and molecular biology.
Davies et al. (Thu,) conducted a review in Intimal hyperplasia. A review of intimal hyperplasia details its pathology, physiology, pharmacology, cell biology, and molecular biology as a chronic structural lesion developing after vessel wall injury.