Early Experience with Beta-Lactam Therapeutic Drug Monitoring in an Outpatient Parenteral Antimicrobial Therapy (OPAT) Program

Key Points

• This research aims to explore the use of beta-lactam therapeutic drug monitoring (TDM) in outpatient care to optimize dosing and reduce toxicity.
• Descriptive analysis of beta-lactam TDM implementation in an outpatient parenteral antimicrobial therapy program.
• Cases of selected patients were reviewed to illustrate the feasibility of TDM.
• Beta-lactam TDM informed dose adjustments leading to improved therapeutic outcomes.
• Emerging lessons from the cases indicated successful toxicity mitigation strategies.