Greater left atrial roof thickness and its increase 1 day after circumferential pulmonary vein ablation predicted early recurrence of atrial fibrillation (P<0.05).
Cohort (n=56)
p-value: p=<0.05
BACKGROUND: Inflammatory responses following atrial fibrillation (AF) ablation may aggravate arrhythmogenic activity and cause an early recurrence of AF (ERAF). METHODS AND RESULTS: In 56 patients who underwent circumferential pulmonary vein ablation (CPVA) for paroxysmal AF, cardiovascular magnetic resonance imaging (CMRI) was evaluated in 5 subdivided left atrial (LA) regions before the CPVA and at 1 day and 1 month after. At a mean of 7+/-10 days after the CPVA, 23 patients (41%) developed 1 or more episodes of AF (ERAF group), while 33 patients (59%) remained free from AF during the first month of follow up (no-ERAF group). LA wall thickness increased 1 day after the CPVA in both groups, as demonstrated by high T2-weighted signal. The LA roof thickness and its increase, however, were greater in the ERAF group than in the no-ERAF group (P<0.05). Regions of delayed enhancement (DE) were also frequently detected in both groups, but the total number of DE regions did not differ between the 2 groups. The thickening of the LA wall associated with a high T2-weighted signal resolved within 1 month. No significant difference between the 2 groups was found in any of the CMRI parameters before or 1 month after CPVA. CONCLUSIONS: Thickening of the LA roof shortly after CPVA may predict an ERAF.
Yokokawa et al. (Fri,) conducted a cohort in Paroxysmal atrial fibrillation (n=56). Circumferential pulmonary vein ablation (CPVA) vs. No early recurrence of AF (no-ERAF) was evaluated on Left atrial roof thickness and its increase 1 day after CPVA (p=<0.05). Greater left atrial roof thickness and its increase 1 day after circumferential pulmonary vein ablation predicted early recurrence of atrial fibrillation (P<0.05).
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