From gene discovery to synthetic biology: recent advances in the biosynthesis of oleanane-type pentacyclic triterpenoids

Key Points

• This review aims to summarize the latest advancements in the biosynthesis of oleanane-type triterpenoids.
• Review of recent literature on biosynthetic enzymes and regulatory networks
• Discussion of synthetic biology strategies
• Evaluation of AI-driven predictive optimization methods for production
• New biosynthetic enzymes and regulatory networks have been identified for triterpenoid production.
• Synthetic biology strategies show promise for enhancing sustainability in production.
• AI-driven optimization techniques suggest more efficient pathways for biosynthesis.