Optimizing imaging methodology across echocardiography, CMR, CT, and nuclear imaging is essential to translating technical advances into consistent improvements in hypertrophic cardiomyopathy care.
This review emphasizes the need for standardization and multimodality integration of imaging techniques to improve clinical decision-making in hypertrophic cardiomyopathy.
Abstract Imaging is fundamental to the evaluation and management of hypertrophic cardiomyopathy, yet substantial variability in acquisition, analysis, and interpretation persists across modalities. These methodological inconsistencies limit reproducibility, hinder multimodality integration, and complicate the use of imaging findings in clinical decision-making. This review examines key technical challenges and optimization strategies across contemporary imaging modalities used in HCM. We discuss practical considerations in echocardiography for assessing dynamic left ventricular outflow tract obstruction and mitral valve mechanisms; methodological uncertainties in cardiac magnetic resonance (CMR), including fibrosis quantification, parametric mapping, and perfusion imaging; evolving applications of computed tomography (CT) for detailed anatomic assessment, coronary evaluation, and procedural planning; and the selective role of nuclear imaging for quantifying microvascular dysfunction and evaluating phenocopies. Emphasis is placed on sources of measurement variability, current limitations, and opportunities for standardization and automation. We further highlight the importance of integrating multimodality imaging within tailored clinical workflows with complementary, rather than sequential use of imaging techniques. Optimizing imaging methodology is essential to translating technical advances into consistent and meaningful improvements in the care for patients with HCM.
This study, published in a European Heart Journal publication, explores the use of large language models in the peer review process for cardiology manuscripts. The findings on the quality and speed of AI-generated reviews are highly topical and have implications for the future of scientific publishing.
Keen et al. (Tue,) conducted a review in Hypertrophic cardiomyopathy. Imaging techniques (echocardiography, CMR, CT, nuclear imaging) was evaluated. Optimizing imaging methodology across echocardiography, CMR, CT, and nuclear imaging is essential to translating technical advances into consistent improvements in hypertrophic cardiomyopathy care.