The article provides an overview of the biological role of essential elements, including their important function in implementing adaptation mechanisms in various climatic conditions, particularly in the Aral Sea region, where the human body experiences adverse effects of natural and anthropogenic factors. It has been established that the condition of the skin, which determines the ability of the body to function normally under changing environmental conditions, largely depends on the body's supply of micro- and macroelements, while the manifestation of an excess or deficiency of vital microelements can be a pathognomonic symptom of these disorders.
G. U. Zhanabaeva*1,3, Z. I. Akhmed Zhanova2, R. I. Turimbetova1, R. K. Aytnazarova1 (Fri,) studied this question.