HOCM is a rare, likely hereditary disease characterized by marked ventricular septal hypertrophy that can lead to congestive heart failure or sudden death.
Two cases of hypertrophic obstructive cardiomyopathy (HOGM) seen among a total of 11,141 medico‐legal autopsies are reported, A review of the literature is presented; it shows that the disease occurs rarely and probably is hereditary. The manner of transmission is not known. Pathoanatomically, the diagnosis of HOCM ought to be based on macroscopical as well as microscopical findings. In the view of the authors the greater weight should be placed on the macroscopical findings as the microscopical abnormalities are not necessarily pathognomonic and vary in incidence. The marked and dominant hypertrophy of the ventricular septum is the characteristic finding in this disease. The cause of death is often congestive heart failure, but frequently death is sudden and unexpected.
Simonsen et al. (Sun,) studied this question.