In Japanese men aged 65 years, a BMI of <18.5 (OR 4.08) and ≥25.0 (OR 1.98) significantly increased the risk of developing hypertension over 5 years compared to a BMI of 18.5-22.9.
Cohort (n=1,003)
No
Does abnormal BMI at age 65 increase the risk of developing hypertension over the subsequent 5 years in Japanese individuals?
Both leanness (BMI <18.5) and overweight/obesity (BMI ≥23.0) at age 65 are associated with an increased risk of developing hypertension over the subsequent 5 years in Japanese men.
Effect estimate: OR 4.08 (95% CI 1.32-12.4)
p-value: p=<0.05
OBJECTIVE: This study aimed to investigate the association between BMI at 65 years of age and the development of hypertension during the subsequent five years. METHODS: A total of 1,003 participants (65 years of age) who had no history of myocardial infarction and/or hypertension at baseline health check-ups (1996-2005) and participated in a secondary health check-up when the subjects reached 70 years of age were analyzed. RESULTS: Using fully adjusted models, men with a BMI of <18.5 odds ratio (OR), 4.08; 95% confidence interval (CI), 1.32-1.83, BMI of 23.0-24.9 (OR, 2.00; 95% CI, 1.18-3.40) and BMI of ≥25.0 (OR, 1.98; 95% CI, 1.10-3.56) were found to be at higher risk of developing hypertension than did those with a BMI of 18.5-22.9. CONCLUSION: Leanness or being overweight/obese at age 65 increases the risk of subsequent hypertension.
Ukawa et al. (Thu,) conducted a cohort in Hypertension (n=1,003). Body Mass Index <18.5 (Leanness) vs. Body Mass Index 18.5-22.9 was evaluated on Development of hypertension at 70 years of age (OR 4.08, 95% CI 1.32-12.4, p=<0.05). In Japanese men aged 65 years, a BMI of <18.5 (OR 4.08) and ≥25.0 (OR 1.98) significantly increased the risk of developing hypertension over 5 years compared to a BMI of 18.5-22.9.
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