Granulocyte colony-stimulating factor and stem cell factor improve endogenous repair after myocardial infarction.
Does granulocyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) improve left ventricular function and cellular repair in a reperfusion model of myocardial infarction?
In a preclinical reperfusion model of myocardial infarction, G-CSF and SCF are investigated for their potential to improve left ventricular function and endogenous cellular repair.
Absolute Event Rate: 0% vs 0%
Objective The aims of this study were, first, to determine if granulocyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) improved left ventricular function in the setting of a reperfusion model of myocardial infarction (MI) and, second, to evaluate the effects of G-CSF/SCF on cellular repair and, in particular, the fate of bone marrow cells homing to the site of tissue injury.
Kanellakis et al. (Fri,) reported a other. Granulocyte colony-stimulating factor and stem cell factor improve endogenous repair after myocardial infarction.