A Myocardial Performance Index > 0.55 was strongly associated with an increased risk of death or cardiovascular hospitalizations (RR 18.7; 95% CI 16.6-20.7; P<0.005).
Cohort (n=112)
Does the myocardial performance index (MPI) predict death or cardiovascular hospitalizations in ambulatory patients with heart failure?
Effect estimate: RR 18.7 (95% CI 16.6-20.7)
p-value: p=< 0.005
BACKGROUND: Many echocardiographic parameters have been proposed for the assessment of the patients with heart failure (HF). Recently, the myocardial performance index (MPI) has been shown to be an accurate index of myocardial function. We assessed the correlation with other clinical and echocardiographic measurements and the prognostic value of MPI in patients with HF. METHODS AND RESULTS: The MPI was assessed in 112 consecutive patients with persistent symptoms of HF (II-III NYHA class), sinus rhythm, LV systolic dysfunction (defined by an ejection fraction 0.55 (median value) and medium to severe mitral regurgitation were associated with a relative risk of cardiovascular events of 18.7 (95% confidence interval CI, 16.6-20.7; P < 0.005) and of 3.03 (95% CI, 2-4.1; P = 0.035), respectively. CONCLUSIONS: In our patients with HF, MPI was the best predictor of cardiovascular events. Mitral regurgitation was the only other variable which had an additive prognostic value at multivariate analysis.
Vizzardi et al. (Fri,) conducted a cohort in Heart Failure (n=112). Myocardial Performance Index (MPI) was evaluated on Incidence of death or cardiovascular hospitalizations (RR 18.7, 95% CI 16.6-20.7, p=< 0.005). A Myocardial Performance Index > 0.55 was strongly associated with an increased risk of death or cardiovascular hospitalizations (RR 18.7; 95% CI 16.6-20.7; P<0.005).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: