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Recent technical improvements in grey-scale ultrasound imaging have resulted in the visualization of the internal consistency of soft tissues. This permits the diagnosis of diffuse pathology and detection of small space-occupying lesions. The new technique can be used with advantage in the currently accepted obstetrical applications for ultrasound imaging as well as for new non-obstetrical applications. The method has been found to be a most informative, non-intrusive means for investigating hepatobiliary disease and for the differential diagnosis of chronic splenomegaly.
Taylor et al. (1976) studied this question.