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ColabFold offers accelerated protein structure and complex predictions by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold’s 40 - 60× faster search and optimized model use allows predicting close to a thousand structures per day on a server with one GPU. Coupled with Google Colaboratory, ColabFold becomes a free and accessible platform for protein folding. ColabFold is open-source software available at github.com/sokrypton/ColabFold . Its novel environmental databases are available at colabfold.mmseqs.com Contact milot.mirdita@mpibpc.mpg.de , so@fas.harvard.edu , martin.steinegger@snu.ac.kr
Mirdita et al. (Sun,) studied this question.
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