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Director of the National Heart Institute, initiated a major clinical research program in 1966 to improve the treatment of patients with acute myocardial infarc- tion and our understanding of the disease. In addition to the support of specific research, a network of myocardial infarction research units was envisioned with a shared purpose in the accurate description of the disease, its natural history, and response to therapy. It was largely these latter considerations which led Dr. Grant and his successors to allocate sufficient monies so that each Myocardial Infarction Research Unit could develop a sophisticated computer-based information man- agement system. Certain of the MIRUs focused on the development of systems for acquiring physiologic data from patients while others worked on systems for the collection, storage, and handling of both discrete and categoric data. The MIRU directors and leaders at the National Heart and Lung Institute felt an important responsibility to explore the potential offered by computer systems to develop something which would have an impact on the study of cardiovascular disease-an impact greater than that which might be anticipated as the result of any single research project or collection of projects.
Wallace et al. (Thu,) studied this question.