Ambulatory and home blood pressure levels were significantly associated with silent cerebrovascular lesions and carotid atherosclerosis (all P<0.05), whereas casual/clinic blood pressure was not.
Observational (n=1,007)
Do ambulatory and home blood pressure measurements better predict subclinical cerebrovascular diseases compared to casual/clinic measurements in adults aged ≥55 years?
Ambulatory and home blood pressure monitoring are superior to clinic measurements for predicting subclinical cerebrovascular target organ damage, with each method predicting different specific types of damage.
p-value: p=<0.05
The usefulness of ambulatory, home, and casual/clinic blood pressure measurements to predict subclinical cerebrovascular diseases (silent cerebrovascular lesions and carotid atherosclerosis) was compared in a general population. Data on ambulatory, home, and casual/clinic blood pressures and brain MRI to detect silent cerebrovascular lesions were obtained in 1007 subjects aged ≥55 years in a general population of Ohasama, Japan. Of the 1007 subjects, 583 underwent evaluation of the extent of carotid atherosclerosis. Twenty-four-hour, daytime, and nighttime ambulatory and home blood pressure levels were closely associated with the risk of silent cerebrovascular lesions and carotid atherosclerosis (all P<0.05). When home and one of the ambulatory blood pressure values were simultaneously included in the same regression model, each of the ambulatory blood pressure values remained a significant predictor of silent cerebrovascular lesions, whereas home blood pressure lost its predictive value. Of the ambulatory blood pressure values, nighttime blood pressure was the strongest predictor of silent cerebrovascular lesions. The home blood pressure value was more closely associated with the risk of carotid atherosclerosis than any of the ambulatory blood pressure values when home and one of the ambulatory blood pressure values were simultaneously included in the same regression model. The casual/clinic blood pressure value had no significant association with the risk of subclinical cerebrovascular diseases. Although the clinical indications for ambulatory blood pressure monitoring and home blood pressure measurements may overlap, the clinical significance of each method for predicting target organ damage may differ for different target organs.
Hara et al. (Tue,) conducted a observational in Subclinical cerebrovascular diseases (n=1,007). Ambulatory and home blood pressure measurements vs. Casual/clinic blood pressure measurements was evaluated on Subclinical cerebrovascular diseases (silent cerebrovascular lesions and carotid atherosclerosis) (p=<0.05). Ambulatory and home blood pressure levels were significantly associated with silent cerebrovascular lesions and carotid atherosclerosis (all P<0.05), whereas casual/clinic blood pressure was not.