Malignant lymphoma in African children.I. A clinical syndrome

I to a group of sarcomas seen in an undue frequency in children at Mulago Hospital, Kampala, Uganda.4Without specifically classifying their histological identity, it was suggested that they were similar to a "round cell sarcoma" often seen as a multiple tumor in the abdomen of children in the same age group and that they were probably derived from a primitive element of the reticuloendothelial system.In 1959, one of us, (G.T.O'C.) with Davie~,~g in a review of all the malignant tumors of children recorded in the Kampala Cancer Registry at Kampala, Uganda, confirmed that these jaw and abdominal tumors were indeed histologically identical, that they were malignant lymphomas, and that they constituted about 50% of all malignant tumors seen in African children.It has become increasingly apparent that these tumors may be readily recognized as a well defined clinical syndrome and moreover that they represent a distinct and unique