Office systolic blood pressure showed a significant linear correlation with ambulatory (r=0.78) and home (r=0.70) systolic blood pressure in patients with heart failure.
Observational (n=902)
In patients with heart failure, the relationship between office and out-of-office blood pressure differs from the general population, with an office BP of 140/90 mmHg corresponding to lower out-of-office values (approximately 126/78 mmHg).
Effect estimate: r = 0.78
Objective: Although hypertension guidelines have defined home blood pressure (HBP) and ambulatory blood pressure (ABP) values that correspond to specific office blood pressure (OBP) thresholds, it remains unclear whether these out-of-office BP correspondences are comparable in patients with heart failure (HF). This study aims to elucidate the relationship between OBP and out-of-office BP in individuals with HF. Design and method: A total of 902 HF patients from the Out-of-Office Blood Pressure Measurements in Patients with Heart Failure Registry Study (OOBPM-HF study) were included. Linear regression models were used to explore the relationships between OBP and both HBP and ABP. The HBP and ABP values corresponding to specific OBP values were calculated. Additionally, the coincident OBP and out-of-office BP values were computed. The white coat effect (WCE) was defined as the difference between office systolic BP and daytime ambulatory systolic BP. Moreover, LASSO regression and machine learning models were employed to identify the determinants of WCE in HF patients. Results: OBP showed a significant linear correlation with both HBP and ABP, with stronger Pearson correlation coefficients observed for systolic BP (r = 0.78 for OBP–ABP; r = 0.7 for OBP–HBP) than for diastolic BP (r = 0.65 for OBP–ABP; r = 0.52 for OBP–HBP). Notably, the slopes of the relationships between OBP and ABP were steeper than those between OBP and HBP. The corresponding HBP and ABP values for an OBP of 140/90 mmHg were 126.1/79.1 mmHg and 125.7/78.0 mmHg, respectively. The coincident values for OBP and HBP were 113.9/71.2 mmHg, while those for OBP and ABP were 110.4/66.2 mmHg. The mean WCE in HF patients were 8.7 mmHg. The most crucial predictor for WCE was office systolic BP, followed by medical insurance, HF type, sex, total cholesterol, diabetes, educational level, marital status, treatment, triglyceride, and estimated glomerular filtration rate. Conclusions: In patients with HF, the relationship between office and out-of-office BP measurements differs from that observed in the general population. Out-of-office BP monitoring is recommended for HF patients to accurately assess their BP profile, which is critical for optimizing guideline-directed medical therapy.
Miao et al. (Fri,) conducted a observational in Heart failure (n=902). Office blood pressure vs. Out-of-office blood pressure (home and ambulatory) was evaluated on Correlation between office blood pressure and out-of-office blood pressure (r = 0.78). Office systolic blood pressure showed a significant linear correlation with ambulatory (r=0.78) and home (r=0.70) systolic blood pressure in patients with heart failure.