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Abstract Glucose and insulin values in plasma after a peroral glucose tolerance test, triglycerides and cholesterol in plasma, body composition and adipose tissue fat cell diameter were determined in nonselected men surviving a myocardial infarction and were compared with the same variables in randomly selected men from the same region of equivalent age. The patients with myocardial infarction were characterized by a diminished glucose tolerance and elevated plasma lipids when compared with controls. The diminished glucose tolerance was more pronounced in patients with signs suggesting severe myocardial damage or complications to the myocardial infarction. Body fat, fat cell size or insulin values during glucose tolerance test were, however, not increased in patients with myocardial infarction. Fat cell size and fasting insulin or the sum of plasma insulin during the glucose tolerance test correlated positively in both groups of older men. Plasma triglycerides showed significant, positive correlations with the sum of insulin and glucose values during the glucose tolerance test. Patients with endogenous hypertriglyceridemia had higher insulin and blood glucose values and more body fat than patients without plasma lipid abnormalities. It was suggested that increased plasma triglycerides in patients with myocardial infarction are combined with decreased glucose tolerance and an increased insulin secretion associated with enlargement of adipose tissue fat cells.
Berchtold et al. (Sat,) studied this question.