Estimates of pulmonary vascular elastance (Ea(PV), Ea*(PV), and PPSV) were significantly correlated with pulmonary vascular resistance (r=0.772, 0.569, and 0.935, respectively; P<.001).
Observational (n=42)
Does pulmonary arterial elastance correlate with pulmonary vascular resistance for estimating right ventricular afterload in patients with systolic heart failure?
Pulmonary vascular elastance calculated from routine right heart catheterization correlates significantly with pulmonary vascular resistance, offering a promising surrogate for assessing right ventricular afterload in systolic heart failure.
Effect estimate: r=0.772, 0.569, and 0.935
p-value: p=<.001
Assessment of right ventricular afterload in systolic heart failure seems mandatory as it plays an important role in predicting outcome. The purpose of this study is to estimate pulmonary vascular elastance as a reliable surrogate for right ventricular afterload in systolic heart failure. Forty-two patients with systolic heart failure (ejection fraction <35%) were studied by right heart catheterization. Pulmonary arterial elastance was calculated with three methods: Ea(PV) = (end-systolic pulmonary arterial pressure)/stroke volume; Ea*(PV) = (mean pulmonary arterial pressure - pulmonary capillary wedge pressure)/stroke volume; and PPSV = pulmonary arterial pulse pressure (systolic - diastolic)/stroke volume. These measures were compared with pulmonary vascular resistance (mean pulmonary arterial pressure - pulmonary capillary wedge pressure/CO). All estimates of pulmonary vascular elastance were significantly correlated with pulmonary vascular resistance (r=0.772, 0.569, and 0.935 for Ea(PV), Ea*(PV), and PPSV, respectively; P <.001). Pulmonary vascular elastance can easily be estimated by routine right heart catheterization in systolic heart failure and seems promising in assessment of right ventricular afterload.
Amin et al. (Tue,) conducted a observational in Systolic heart failure (n=42). Pulmonary arterial elastance estimation vs. Pulmonary vascular resistance was evaluated on Correlation between pulmonary vascular elastance estimates and pulmonary vascular resistance (r=0.772, 0.569, and 0.935, p=<.001). Estimates of pulmonary vascular elastance (Ea(PV), Ea*(PV), and PPSV) were significantly correlated with pulmonary vascular resistance (r=0.772, 0.569, and 0.935, respectively; P<.001).