What is the clinical evidence from this study?

Study design: Observational. Population: Patients undergoing echocardiography and coronary angiography (n=28). Intervention: Circumflex artery motion (CXM) vs. Mitral annulus motion (MAM). Primary outcome: Motion amplitude at epicardial vs endocardial sites (p=<0.001).

January 1, 2001

Comparison between Circumflex Artery Motion and Mitral Annulus Motion

Q: What are the key findings of this study?

Circumflex artery motion (epicardial) was significantly higher than mitral annulus motion (endocardial) in patients with normal ejection fraction (p<0.001), but not in those with decreased EF.

Key Result

Circumflex artery motion (epicardial) was significantly higher than mitral annulus motion (endocardial) in patients with normal ejection fraction (p<0.001), but not in those with decreased EF.

Study Design

Type

Observational (n=28)

Structured PICO

How does circumflex artery motion compare to mitral annulus motion in patients with normal versus decreased ejection fraction?

Population

28 patients examined by echocardiography and coronary angiography, including 13 with normal ejection fraction and 13 with decreased ejection fraction.

Exposure

Measurement of circumflex artery motion (CXM) and epicardial motion amplitude

Comparator

Measurement of mitral annulus motion (MAM) and endocardial motion amplitude

Outcome

Comparison of motion amplitude between MAM and CXM, and between endocardial and epicardial sites at the basal lateral part of the atrioventricular planesurrogate

Circumflex artery motion represents epicardial atrioventricular plane motion and differs from mitral annulus motion (endocardial), which must be considered when assessing left ventricular systolic function.

Main Result

p-value: p=<0.001

Abstract

OBJECTIVE: To compare mitral annulus motion (MAM) with circumflex artery motion (CXM) and the motion amplitude at an endocardial site (representing MAM) with an epicardial site (representing CXM) at the most basal lateral part of the atrioventricular plane (AVP). DESIGN: MAM and CXM were obtained in 28 patients examined by echocardiography and coronary angiography. The motion amplitude epicardially and endocardially was recorded by echocardiography in 13 patients with normal ejection fraction (EF) (> or = 0.50) and in 13 patients with decreased EF (<0.50). RESULTS: CXM was higher than MAM in most patients with normal EF but lower than MAM in most patients with decreased EF. The motion amplitude epicardially was significantly higher (p < 0.001) than endocardially in patients with normal EF. while there was no significant difference in patients with decreased EF. CONCLUSION: CXM represents the motion of the epicardial part of the AVP and differs from MAM, which represents the endocardial part of the wall. This must be considered when CXM is used for assessment of left ventricular systolic function.

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