Insulin-dependent diabetic children and adolescents exhibited abnormal postexercise systolic function, including reduced fractional shortening (0.37 vs. 0.43) compared to nondiabetic controls.
Case-Control
Does dynamic exercise reveal abnormal cardiac function by postexercise echocardiography in insulin-dependent diabetic children and adolescents compared to nondiabetic controls?
Postexercise echocardiography can reveal subclinical systolic dysfunction in asymptomatic insulin-dependent diabetic children and adolescents.
Absolute Event Rate: 0.37% vs 0.43%
We evaluated the cardiac response to dynamic exercise in a group of otherwise healthy insulin-dependent older children and adolescents and in a nondiabetic control group by postexercise echocardiography. Both groups had similar left ventricular function at rest. After exercise we found abnormalities in the indicators of systolic function, fractional shortening (0.37 vs. 0.43) and rate-corrected velocity of circumferential fiber shortening (2.80 vs. 3.35 circumferences/s). In addition, we found an association of flattened interventricular septal motion with finger contractures in the diabetic subjects. Echocardiographic abnormalities in asymptomatic young diabetic adolescents can be elucidated by postexercise echocardiography. Postexercise echocardiography is a noninvasive procedure that can easily be done in the adolescent population and is useful for evaluating subclinical cardiomyopathy.
Baum et al. (Fri,) conducted a case-control in Insulin-dependent diabetes. Insulin-dependent diabetes vs. Nondiabetic control group was evaluated on Postexercise fractional shortening. Insulin-dependent diabetic children and adolescents exhibited abnormal postexercise systolic function, including reduced fractional shortening (0.37 vs. 0.43) compared to nondiabetic controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: