Physician stated management of atrial fibrillation diverged from ACC/AHA/ESC guidelines, particularly regarding first-line drug selection in patients with structural heart disease.
Observational (n=5,604)
Yes
What are physicians' theoretical approaches to rhythm and rate control in recently diagnosed atrial fibrillation patients?
Physician-stated management of atrial fibrillation frequently diverges from ACC/AHA/ESC guidelines, particularly in the use of amiodarone as a first-line rhythm control agent in patients with structural heart disease.
BACKGROUND: The Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation (RecordAF) study is the first worldwide, prospective, survey of real-life management of atrial fibrillation (AF) in recently diagnosed patients (n = 5604) with a 1-year follow-up. HYPOTHESIS: Surveys of AF management have identified a divergence between guidelines and clinical practice, and an overinterpretation of guidelines in low-risk patients. METHODS: : Physicians' theoretical approaches to rhythm and rate control were investigated using a pre-study questionnaire. RESULTS: One cardiologist, from each of the 583 sites in 6 regions, completed a questionnaire on their practice and management of AF patients. In AF patients with structural heart disease (SHD), amiodarone was the most frequent choice of first-line rhythm control agents in all regions. Amiodarone or sotalol tended to be the preferred second-line rhythm control agents, 1 exception being Central/South America. beta-Blockers were the first-line rate control agents for patients with AF and SHD in all regions, and calcium channel blockers and cardiac glycosides were the most common second-line rate control treatments in all regions, except Asia. In lone AF patients, propafenone (30.6%), flecainide (24.1%), and amiodarone (21.7%) were the most common global choices of first-line rhythm control, and amiodarone or sotalol were the preferred second-line rhythm control agents, 1 exception being Central/South America. CONCLUSIONS: These results highlight points of divergence from the American College of Cardiology (ACC)/ American Heart Association (AHA)/European Society of Cardiology (ESC) guidelines for the management of AF in terms of first-line drug selection in patients with associated SHD or coronary artery disease.
Kowey et al. (Mon,) conducted a observational in Atrial Fibrillation (n=5,604). Physician stated management of atrial fibrillation was evaluated on Physicians' theoretical approaches to rhythm and rate control. Physician stated management of atrial fibrillation diverged from ACC/AHA/ESC guidelines, particularly regarding first-line drug selection in patients with structural heart disease.