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July 1, 2022Current Atherosclerosis Reports70 citationsOpen Access

Biology, Bias, or Both? The Contribution of Sex and Gender to the Disparity in Cardiovascular Outcomes Between Women and Men

SGSarah GauciSCSusie CartledgeJRJulie Redfern

Key Result

Sex and gender differences contribute to the inequality in risk, presentation, and treatment of cardiovascular disease in women compared to men.

Structured PICO

P
Population
Men and women with or at risk for cardiovascular disease

Sex and gender differences contribute to disparities in cardiovascular disease outcomes, highlighting the need for gender bias education, patient-centered care, and inclusive research.

Abstract

PURPOSE OF REVIEW: Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide for both men and women. However, CVD is understudied, underdiagnosed, and undertreated in women. This bias has resulted in women being disproportionately affected by CVD when compared to men. The aim of this narrative review is to explore the contribution of sex and gender on CVD outcomes in men and women and offer recommendations for researchers and clinicians. RECENT FINDINGS: Evidence demonstrates that there are sex differences (e.g., menopause and pregnancy complications) and gender differences (e.g., socialization of gender) that contribute to the inequality in risk, presentation, and treatment of CVD in women. To start addressing the CVD issues that disproportionately impact women, it is essential that these sex and gender differences are addressed through educating health care professionals on gender bias; offering patient-centered care and programs tailored to women's needs; and conducting inclusive health research.

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Cite This Study

Gauci et al. (2022) conducted a review in Cardiovascular disease. Sex and gender differences vs. Men was evaluated. Sex and gender differences contribute to the inequality in risk, presentation, and treatment of cardiovascular disease in women compared to men.

synapsesocial.com/papers/6a21b6c7c9834130fef1b278https://doi.org/10.1007/s11883-022-01046-2
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